SCIENCE

AI-designed drug enters clinical trials

By Sanjana Shankar

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AI-designed drug

A drug, the first to be designed and discovered completely with the help of AI, is now entering into phase 2 clinical trials.

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IPF

This drug, which is developed by Hong Kong-based Insilico Medicine, is targeted at a rare chronic lung disease called idiopathic pulmonary fibrosis (IPF).

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Process

Insilico Medicine first identified proteins linked to the IPF disease and then screened substances that could inhibit these proteins to develop the drug.

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Phase 1 trials

The company has already completed the phase 1 trials of the IPF drug in New Zealand and China with "favorable results."

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Phase 2 trials

The phase 2 clinical trials of the IPF drug will aim to evaluate the efficacy of the drug and estimate its safety profile. It will include 60 participants from China and US.

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