This is a period of time that you takeoff from your school, workplace, or home to enjoy a period of travel from one place to another. It is long and could be relatively more expensive.
Holiday
A holiday is generally seen as something to celebrate and take some time off doing so. While vacations are planned, holidays can be sudden and are shorter than the former.
Staycation
While for some, staycation means staying in and enjoying their local area, for most it includes short trips in and around their hometown including overnight halts at hotels or homestays.
Getaway
Getaway simply means an escape. They are usually short and are done at places that are offbeat. It can be planned instantly, involves minimal travel usually by road, and is also less costly.
Break
A break is a period that you take off from your daily work. It could span from a few hours to some days. They aren't necessarily about travel and are usually spent staying home.