Is Meftal, instant painkiller for headaches and period cramps, safe
Meftal, a widely used non-steroidal anti-inflammatory medication, has recently come under scrutiny for safety concerns highlighted by the Indian Pharmacopoeia Commission. Marketed under the name Mefenamic acid, this drug is known to trigger adverse reactions, including the DRESS syndrome. The Indian government has released a warning, asking medical professionals and patients to closely monitor any potential side effects.
Understanding the DRESS Syndrome
DRESS syndrome, or Drug Rash with Eosinophilia and Systemic Symptoms, is a severe allergic reaction linked to specific medications, including nonsteroidal anti-inflammatory drugs (NSAIDs) like Meftal. This potentially life-threatening condition manifests as fever, skin rashes, and lymphadenopathy, and can affect internal organs. With an estimated 10% mortality rate, the importance of recognizing and preventing this reaction is paramount.
Reporting and monitoring
In response to this, healthcare professionals and consumers are urged to closely monitor potential adverse drug reactions associated with Meftal. The alert instructs individuals to report any such reactions promptly to the national coordination center of the Pharmacovigilance Programme of India (PvPI). Reporting can be done through the official website or the dedicated mobile app, emphasizing the importance of proactive reporting for effective monitoring.
Prevalence and brands
Meftal and its equivalents, like Mefkind P from Mankind Pharma, Ponstan from Pfizer, Mefanorm from Serum Institute, and Ibuclin P from Dr. Reddy, are widely used in India for a variety of ailments, even though they can only be obtained with a prescription. The alert serves as a reminder for healthcare providers and consumers to exercise caution and consider alternative medications when necessary.
Expert perspectives on DRESS syndrome
Medical experts acknowledge that While the overall incidence of DRESS syndrome is relatively low, the severity of this reaction necessitates caution. Despite reassurances from some medical professionals about their experiences with Meftal, the importance of individual variations in drug response is highlighted. This imposes the need for careful consideration, monitoring, and informed decision-making regarding the use of Meftal.
